The KRAS gene is a substance involved in the enzyme protein of GTP that plays an important role in the signaling system associated with cell differentiation, proliferation and survival. A mutation in the KRAS gene family can be the first sign of a tumor (cancer).
Coronavirus infection-19 is a severe respiratory syndrome caused by SARS-CoV-2. The first cases were reported in December 2019. It became a pandemic as it spread around the world. A notable variant of the coronavirus appeared in late 2020. In January 2021, several powerful variations appeared, including SARS-CoV-2 alpha variations, SARS-CoV-2 beta variations, and SARS-CoV-2 delta variations.
The signal pathway system of sphingosine kinase/spingosine1-phosphate is associated with various cellular processes, such as cell proliferation and survival. Sphingosine 1-phosphate (S1P) is a lipid mediator that regulates cell proliferation, apoptosis, calcium homeostasis, and vascular growth. It has been confirmed that SphK is over-expressed in many solid cancers, particularly the over-expression of Sphk1 is associated with the survival rate of cancer patients.
The MAPK signaling system, a group containing ASK1, is activated primarily by phosphorylation reactions by stress outside the cell and is involved in controlling a variety of conditions, including cancer, diabetes and degenerative brain diseases.
ENPP1 has emerged as a critical phosphodiesterase that degrades the stimulator of interferon genes (STING) ligand, cyclic GMP-AMP (cGAMP)